Description
Transcription factor that binds specifically to the RAS-responsive elements (RRE) of gene promoters (PubMed: 9305772, PubMed: 15067362, PubMed: 8816445, PubMed: 10390538, PubMed: 17550981). Represses the angiotensinogen gene (PubMed: 15067362). Negatively regulates the transcriptional activity of AR (PubMed: 17550981). Potentiates the transcriptional activity of NEUROD1 (PubMed: 12482979). Promotes brown adipocyte differentiation (By similarity). May be involved in Ras/Raf-mediated cell differentiation by enhancing calcitonin expression (PubMed: 8816445)